Laboratory services

List of laboratory services

Species and characteristics of the models:

Outbred and inbred rats with a minimum weight of 200g, pregnant females (from day 9-10), mice (jugular and non-vascular catheters on the digestive tract).

Description of our service

Catheterization can be used for injecting substances (non-vascular catheter except the bile duct catheter) or for sampling (any other type of catheter).

Non-vascular catheters:

  • Bile duct
  • Stomach (injection)
  • Duodenum (injection)
  • Jejunum (injection)
  • Ileum (injection)
  • Colon (injection)
  • Intra-peritoneal (injection)
  • Bladder

Vascular catheters:

  • Jugular vein
  • Femoral vein
  • Carotid artery
  • Femoral artery

Our method

The surgeries are performed under anesthesia with the combined use of anesthetic and analgesic (a2-adrenergic receptor agonist) drugs.

Our implanted catheters are commonly made of polyurethane or silicone (for vascular catheters only).

For vascular catheters, we primarily inject a blocking solution of PVP-heparin or heparin glucose + PVP.

Recommandations - Upon receipt of the animals:

  • Allow only one animal per cage (use a high cage).
  • Rinse catheters upon receipt than every 2nd day.
  • For the double bile duct catheterization, rinse the duodenal catheter only.

Possible options

  • Catheterization of specific-material catheters according to your protocols.
  • Injection of specific blocking solutions.
  • Fixing catheters using specific systems such as Vascular Access Harness (VAH) or Button tether.
  • Double catheterization.
  • Briefing on maintenance and verification of catheters.
  • Performing surgery with a SOPF status.

Our added value

  • Traceability of interventions.
  • Specific perioperative care for each type of surgery.
  • Optimal conditions of the operated animals during shipments, thanks to our dedicated and internal transport service.
  • Ethical review process by our IACUC (MESR No. 078).

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