Research models

List of models

B6CBAF1
Nomenclature: B6CBAF1/JRj

Type: Hybrid mouse
Colour and related genotype: Agouti mouse, A/a, Pde6brd1/+ MHC: Haplotype H2b/k
Origin: from ♀ C57BL/6JRj and ♂ CBA/JRj (from JANVIER LABS)
Breeding: Easy to rear, good maternal instinct

Fields of research

  • Genetic
  • Transgenesis
  • Transplantation

Description of our model

These F1 hybrids are the result of a cross between a C57BL/6JRj female and a CBA/JRj male. F1 hybrids are heterozygous at every locus (provided that the parental strains have different alleles). As is the case with inbred strains, they are genetically and phenotypically uniform.

F1 hybrids are often used for their hybrid vigour (resistance and acitivity). They are especially interesting as genetic background (vigour and repeatability of genetic inheritance) for harmful phenotype models, for tissue transplantation, to determine mechanisms of inheritance, to create or improve expression of polygenic disease.

F1 hybrid females are used at JANVIER LABS’s as surrogate mothers for embryo transfer thanks to their maternal qualities.

Our added value

  • The « JANVIER LABS Genetic Policy », a specific programme, guarantees the genetic repeatability of our hybrid models.
  • Animals with the SPF or SOPF standards.
  • A gentling policy for docile and easy-to-handle animals.
  • Optimal stability conditions of our models during shipments, thanks to our dedicated and internal transport service.
  • A scientific support with a team of Veterinarians and PhD.

Download the corresponding health monitoring reports

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